The Bodenmiller group develops and applies methods to analyse human tissues spatially and at the single cell level, and to understand disease states. In particular, they study cancer tissue to make discoveries that could improve treatment.

The Sallusto lab is focused on the understanding of the mechanisms that control T cell priming and regulate cytokine production and homing capacities. These questions are addressed primarily in the human system, where they combine the ex vivo analysis of memory T cell subsets with in vitro priming of naive T cells.

The Translational Neuromodeling Unit is an interdisciplinary institution with the mission to translate advances in computational neuroscience into tools for clinical practice. The TNU assembles computational scientists and clinicians under one roof and operates a dedicated research clinic for evaluating the diagnostic and prognostic utility of computational assays in prospective patient studies.

The Experimental hematology lab is focused on haematopoietic and immune system development, homeostasis and function, as well as on hemato-lymphoid disease. They aim to gain basic knowledge and to provoke practical new strategies for clinical intervention in states of infection, immunodeficiency, autoimmunity, malignancy, and transplantation of hematopoietic cells.

The Aceto group is interested in understanding the fundamental molecular mechanisms that drive cancer and its metastatic progression, with a particular focus on the analysis of circulating tumor cells.

The Binder lab is studying the adaptive immune system to understand B and T cell biology in health and disease. They are especially interested in immune repertoires and focus on immunotherapy of solid tumors as well as the biology and targeting of lymphoma.

The overall goals of Prof. Detmar’s ongoing research are to identify and to characterize molecular targets controlling inflammatory and tumor angiogenesis and lymphangiogenesis.